Some people take aspirin or ibuprofen to treat everyday aches and pains, but how exactly do the different classes of pain relievers work? Learn about the basic physiology of how humans experience pain, and the mechanics of the medicines we’ve invented to block or circumvent that discomfort.
Watch a video about the pain relievers and choose the correct answers.
1. What is the difference between regular nerve cells and nociceptors?
a) Nociceptors only fire when cells are damaged.
b) Nociceptors only fire when cells are in danger of damage, or are being damaged.
c) Nociceptors only fire when prostaglandins are present.
d) Nociceptors only fire when you haven’t taken any painkillers.
2. Explain why we feel pain. In your answer, consider what life would be like if we did not feel pain, and give examples of situations in which pain is helpful.
3. What event triggers the production of chemicals that lower the pain threshold?
a) Burning your tongue
b) Stubbing your toe
c) Listening to Justin Bieber
d) Anything that damages cells
4. Why might aspirin and ibuprofen reduce fever?
a) Because COX-1 and COX-2 raise our body temperature
b) Because prostaglandin H2 raises our body temperature
c) Because arachidonic acid raises our body temperature
d) Because prostaglandin H2 is converted into stuff that raises our body temperature
5. How do painkillers “know” where you’re feeling pain?
a) They don’t know; they just go everywhere
b) They can sense where COX-1 and COX-2 are being produced
c) They don’t know; they only go to your brain and block pain from there
d) They can hear cells screaming
6. What’s the difference between aspirin and ibuprofen?
a) Aspirin deactivates COX-1 and ibuprofen deactivates COX-2
b) Aspirin is a more effective painkiller
c) Ibuprofen is a more effective painkiller
d) Aspirin permanently deactivates COX-1 and COX-2; ibuprofen only temporarily deactivates COX-1 and COX-2
****The example of vocabulary journal :
The creators : Aaron Augenblick, Lisa Thomas Producer George Zaidan Educator Hal Lee Director Iona Nistor Animator